Memory Critical Care
B. breve MCC1274 is a proprietary probiotic strain originally derived from the infant gut and extensively studied for its role in cognitive wellness and healthy aging. Backed by multiple human clinical trials and mechanistic research, B. breve MCC1274 has demonstrated unique potential to support brain health, memory, and overall mental clarity—particularly in older adults. As a clinically validated option for functional foods, dietary
supplements, and medical nutrition, this innovative strain represents a new frontier in gut–brain axis support and cognitive longevity.*
Key Features
- A Human-Residential Bifidobacteria (HRB) strain that has demonstrated safety and efficacy in more than 20 scientific studies (as of March 2025), particularly among older adults experiencing age-related cognitive decline.*
- Shown to support memory function and visuospatial ability by suppressing
brain atrophy in key regions associated with cognitive function within healthy
older adults having mild cognitive impairment (MCI).* - Helps modulate gut microbiota, reduce systemic inflammation, and improve
biomarkers related to brain health through its metabolites, reflecting its
powerful gut–brain axis activity.*
Why Bifidobacterium breve MCC1274?
B. breve MCC1274 is a next-generation probiotic designed to promote cognitive resilience as we age. With strong science backing, and multiple randomized controlled trials and mechanisms rooted in gut-brain axis, it provides a safe,
natural approach to support memory, focus, and emotional well-being—making it a highly innovative solution for healthy aging and brain performance.*
- Featured on ALZFORUM — the only probiotic strain highlighted on this leading Alzheimer’s disease resource.
- World’s First Bifidobacterium proven to help maintain memory with a single live strain.
- Vitafoods Europe Innovative Awards 2025 — Cognitive and Emotional Health Ingredient.
- Award-Winning Innovation — NutraIngredients Asia Award 2023 for Cognitive Function.
- Recognized Excellence — Wellness Food Award 2023 in Japan.
B. breve MCC1274 is ideal for use in:
- Cognitive Health Supplements: Formulate stand-alone or multi-strain probiotic products for memory support and brain health.
- Healthy Ageing Nutrition: Add value to nutritional products aimed at seniors looking to maintain independence and mental acuity.
- Medical Nutrition and Functional Foods: B. breve MCC1274 is suited for advanced formulations targeting early cognitive decline and general neuroprotection.
B. breve MCC1274 is a versatile functional ingredient suitable for a broad range of product formats. Depending on your formulation needs and target demographics, B. breve MCC1274 can be incorporated into:
Legislation can be varied by country when it comes to specific dosage and potential health claims of each strain.
Our regulatory team can help and advise you as to the appropriate individual markets permit. Morinaga’s global regulatory experts are located in all major regions. We are committed to delivering expert advice and practical solutions in order to optimize your company’s success.
The information on this website is intended exclusively for business-to-business purposes and is not intended for end-consumer utilization. It is predicated upon our rigorous research and development endeavors and, to the best of our knowledge, is deemed reliable. Morinaga disclaims any liability arising from the utilization of its products, as the terms of employment are beyond our purview. The business-oriented information furnished herein should not be construed as a substitute for professional counsel. Prior to implementation, manufacturers and marketers are advised to ascertain compliance with local regulatory prerequisites, given that divergent claims may be permissible contingent upon the prevailing regulations in individual countries. This presentation is purely informative in a scientific context and does not constitute claims or marketing notifications within the jurisdiction of the United States.
Explore the Morinaga Probiotics Center to delve into key highlights showcasing the clinical efficacy of B. breve MCC1274.
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