Immune Support
Dairy Free
Gluten Free

Morinaga’s flagship Human-Residential Bifidobacteria (HRB) probiotic strain, B. longum BB536, was originally isolated from a healthy infant in 1969. It stands as a robust and stable strain of Bifidobacterium longum, a beneficial bacterial species naturally present in the human gut.*

Key Features

  • A probiotic strain known for the long history of safe use in food and supplement products in over 30 countries for more than 50 years.*
  • Ranks among the world’s most extensively researched probiotics and supported by more than 240 scientific studies (as of March 2023) that assess B. longum BB536’s effects on a wide range of health areas, including gastrointestinal conditions, immunity, skin, cardiovascular health, and more.*
  • With a well-documented history of health benefits, B. longum BB536 is a proprietary, evidence-based, room-temperature stable strain recognized for its safety, history, and robust body of clinical evidence.*

Why B. longum BB536?

For half a century, B. longum BB536 has been the superior HRB probiotic strain that helps people achieve optimal health from the inside out. This strain stands out as a superior choice for digestive and immune support due to its extensive research, attributes, stability, safety, regulatory approvals, and versatile applications.*


Explore our range of downloadable resources, from whitepapers to infographics and brochures. Gain insights into the crucial role of the gut microbiota, the thriving gut health market, and clinical studies backing B. longum BB536. Learn the potential of B. longum BB536 for infant and children’s health, view life-stage-specific infographics, and gain a comprehensive understanding of HRB probiotics with our brochure.

Immune Support
Dairy Free
Gluten Free

B. longum BB536 is a valued functional ingredient in a diverse range of products. Depending on your needs, we can accommodate a variety of product requests targeted at different consumer segments and health areas.*

Pills, Tablets, Capsules
Sachets, Oil Drops
Ice Cream
Protein Powder
Infant Formula
Granola Bars

Legislation can be varied by country when it comes to specific dosage and potential health claims of each strain. Our regulatory team can help and advise you as to the appropriate individual markets permit. Morinaga’s global regulatory experts are in all major regions. We are committed to delivering expert advice and practical solutions to optimize your company’s success.

The information on this website is intended exclusively for business-to-business purposes and is not intended for end-consumer utilization. It is predicated upon our rigorous research and development endeavors and, to the best of our knowledge, is deemed reliable. Morinaga disclaims any liability arising from the utilization of its products, as the terms of employment are beyond our purview. The business-oriented information furnished herein should not be construed as a substitute for professional counsel. Prior to implementation, manufacturers and marketers are advised to ascertain compliance with local regulatory prerequisites, given that divergent claims may be permissible contingent upon the prevailing regulations in individual countries. This presentation is purely informative in a scientific context and does not constitute claims or marketing notifications within the jurisdiction of the United States.

Explore the Morinaga Probiotics Center to delve into key highlights showcasing the clinical efficacy of B. longum BB536.

Elevate your product quality with science-backed, functional ingredients.